Toplam 434 içerik listeleniyor
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KPDS VE ÜDS’DE ZAMANI DOĞRU KULLANMAK
Daha önceki makale ve yazılarımda da belirttiğim gibi, KPDS, ÜDS, YDS gibi akademik sınavlarda zamanı doğru kullanmak oldukça önemlidir. Bu temel olgu aslında “sınav” kavramının vazgeçilmez unsurlarından biridir. Yani; bir soruyu doğru yapmak kadar o soruyu ne kadar sürede yapabildiğinizde toplamda alacağınız puanı belirleyen önemli unsurlardan biridir. Yaklaşmakta olan ÜDS ve KPDS sınavlarına hazırlanan adaylara tavsiyem, sadece bilgilerini artırmaları...
https://www.biyologlar.com/kpds-ve-udsde-zamani-dogru-kullanmak -
Cells are crawling all over our bodies, but how?
For better and for worse, human health depends on a cell's motility –– the ability to crawl from place to place. In every human body, millions of cells –are crawling around doing mostly good deeds ––– though if any of those crawlers are cancerous, watch out.
https://www.biyologlar.com/cells-are-crawling-all-over-our-bodies-but-how -
First computer program developed to detect DNA mutations in single cancer cells
Researchers at The University of Texas MD Anderson Cancer Center have announced a new method for detecting DNA mutations in a single cancer cell versus current technology that analyzes millions of cells which they believe could have important applications for cancer diagnosis and treatment. The results are published in the April 18 online issue of Nature Methods.
https://www.biyologlar.com/first-computer-program-developed-to-detect-dna-mutations-in-single-cancer-cells-haber-8711 -
Drug-resistant genes spread through environment, not meat products
In the first study to use new methods to track antibiotic resistance through the process of intensively farming and slaughtering cattle, scientists have discovered a "startling" lack of resistance genes in meat.
https://www.biyologlar.com/drug-resistant-genes-spread-through-environment-not-meat-products-haber-8719 -
UW team stores digital images in DNA -- and retrieves them perfectly
Technology companies routinely build sprawling data centers to store all the baby pictures, financial transactions, funny cat videos and email messages its users hoard. But a new technique developed by University of Washington and Microsoft researchers could shrink the space needed to store digital data that today would fill a Walmart supercenter down to the size of a sugar cube. The team of computer scientists and electrical engineers has detailed one of the first complete systems to encode,...
https://www.biyologlar.com/uw-team-stores-digital-images-in-dna-and-retrieves-them-perfectly-haber-8723 -
Study accurately dates coral loss at Great Barrier Reef
Historical and modern photographs of Stone Island taken in a) 1915 (photographer unknown); b) 1994 (photographer A. Elliot © Commonwealth of Australia GBRMPA); c) 2012 (photographer H. Markham); and Bramston Reef taken in d) c.1890 (W. Saville-Kent); e) 1994 (photographer A. Elliot © Commonwealth of Australia GBRMPA); f) 2012 (photographer T. Clark). Landscape features in the background of the images helped to locate the same sites: Gloucester Island (GI) and Cape Gloucester...
https://www.biyologlar.com/study-accurately-dates-coral-loss-at-great-barrier-reef-haber-8729 -
A new genome editing method brings the possibility of gene therapies closer to reality
Researchers from Salk Institute for Biological Studies, BGI, and other institutes for the first time evaluated the safety and reliability of the existing targeted gene correction technologies, and successfully developed a new method, TALEN-HDAdV, which could significantly increased gene-correction efficiency in human induced pluripotent stem cell (hiPSC). This study published online in Cell Stell Cell provides an important theoretical foundation for stem cell-based gene...
https://www.biyologlar.com/a-new-genome-editing-method-brings-the-possibility-of-gene-therapies-closer-to-reality-haber-8766 -
Gene therapy shows promise as hemophilia treatment in animal studies
For the first time, researchers have combined gene therapy and stem cell transplantation to successfully reverse the severe, crippling bleeding disorder hemophilia A in large animals, opening the door to the development of new therapies for human patients.
https://www.biyologlar.com/gene-therapy-shows-promise-as-hemophilia-treatment-in-animal-studies-haber-8768 -
The Genetic Structure of Anatolia: From the Neolithic to the Oghuz Migrations
Anatolia has witnessed many migrations and has been home to a variety of civilizations. The increasing availability of ancient DNA samples from different periods and cultures makes it now possible to examine the genetic changes that have taken place in Anatolia since the Neolithic. The ancient DNA revolution has already dispelled many myths, but myths and legends die hard. Some of the more persistent ones concern the impact of the last migration wave to hit Anatolia, marked by the arrival of...
https://www.biyologlar.com/the-genetic-structure-of-anatolia-from-the-neolithic-to-the-oghuz-migrations -
Cell stress inflames the gut
Over 3.5 million people in Europe and the US suffer from Crohn's disease or ulcerative colitis – the two most common forms of IBD. Chronic bowel inflammation is caused by an overreaction of the immune system to the bacteria which naturally occur in the gut. "This overreaction can come about if, for example, the anti-stress mechanism in the cells of the intestinal mucosa does not function correctly," explains Prof. Dirk Haller of the TUM Chair of Nutrition and Immunology. What Prof. Haller is...
https://www.biyologlar.com/cell-stress-inflames-the-gut -
Tarih öncesi insanlarda Hepatit B virüsü bulunduğu ortaya çıktı
Hepatitis viral partiküllerinin illustrasyonu Kaynak: ISTOCK, SARATHSASIDHARAN
https://www.biyologlar.com/tarih-oncesi-insanlarda-hepatit-b-virusu-bulundugu-ortaya-cikti -
Tarih öncesi insanlarda Hepatit B virüsü bulunduğu ortaya çıktı
Hepatitis viral partiküllerinin illustrasyonu Kaynak: ISTOCK, SARATHSASIDHARAN
https://www.biyologlar.com/tarih-oncesi-insanlarda-hepatit-b-virusu-bulundugu-ortaya-cikti -
Tarih öncesi insanlarda Hepatit B virüsü bulunduğu ortaya çıktı
Hepatitis viral partiküllerinin illustrasyonu Kaynak: ISTOCK, SARATHSASIDHARAN
https://www.biyologlar.com/tarih-oncesi-insanlarda-hepatit-b-virusu-bulundugu-ortaya-cikti -
Hirfanlı Baraj Gölünde Yaşayan Yayın Balığı ( Silurus glanis L.,1758 ) nın Sindirim Kanalı Helmintlerinin Tespiti
Hirfanlı Baraj Gölünde Yaşayan Yayın Balığı ( Silurus glanis L.,1758) nın Sindirim Kanalı Helmintlerinin Tespiti
https://www.biyologlar.com/hirfanli-baraj-golunde-yasayan-yayin-baligi-silurus-glanis-l-1758-nin-sindirim-kanali-helmintlerinin-tespiti -
Coral reefs in Palau surprisingly resistant to naturally acidified waters
Ocean researchers working on the coral reefs of Palau in 2011 and 2012 made two unexpected discoveries that could provide insight into corals' resistance and resilience to ocean acidification, and aid in the creation of a plan to protect them. The team collected water samples at nine points along a transect that stretched from the open ocean, across the barrier reef, into the lagoon and then into the bays and inlets around the Rock Islands of Palau, in the western Pacific Ocean. With each...
https://www.biyologlar.com/coral-reefs-in-palau-surprisingly-resistant-to-naturally-acidified-waters -
Improving the delivery of chemotherapy with graphene
A new study published in IOP Publishing's journal 2D Materials has proposed using graphene as an alternative coating for catheters to improve the delivery of chemotherapy drugs. The research suggests that placing graphene - an extremely thin sheet of carbon atoms - on the internal surfaces of intravenous catheters commonly used to deliver chemotherapy drugs into a patient's body will improve the efficacy of treatments, and reduce the potential of the catheters breaking. The study indicates...
https://www.biyologlar.com/improving-the-delivery-of-chemotherapy-with-graphene -
Pancreas stem cell discovery may lead to new diabetes treatments
Stem cells in the adult pancreas have been identified that can be turned into insulin producing cells, a finding that means people with type 1 diabetes might one day be able to regenerate their own insulin-producing cells. The discovery was made by scientists from the Walter and Eliza Hall Institute and provides further evidence that stem cells don't only occur in the embryo. The ability to produce the hormone insulin is crucial for controlling blood sugar (glucose) levels. In people with...
https://www.biyologlar.com/pancreas-stem-cell-discovery-may-lead-to-new-diabetes-treatments -
New discovery in living cell signaling
A breakthrough discovery into how living cells process and respond to chemical information could help advance the development of treatments for a large number of cancers and other cellular disorders that have been resistant to therapy. An international collaboration of researchers, led by scientists with the U.S. Department of Energy (DOE)'s Lawrence Berkeley National Laboratory (Berkeley Lab) and the University of California (UC) Berkeley, have unlocked the secret behind the activation of the...
https://www.biyologlar.com/new-discovery-in-living-cell-signaling -
New resource makes gene-editing technology even more user friendly
Researchers at Harvard University and the University of California, San Diego, have developed a new user-friendly resource to accompany the powerful gene editing tool called CRISPR/Cas9, which has been widely adopted to make precise, targeted changes in DNA. This breakthrough has the potential to facilitate new discoveries in gene therapies and basic genetics research. The research was published in the July 13 issue of Nature Methods. The study describes an approach to simplify a laborious...
https://www.biyologlar.com/new-resource-makes-gene-editing-technology-even-more-user-friendly -
Stem-cell-based strategy boosts immune system in mice
Raising hopes for cell-based therapies, UC San Francisco researchers have created the first functioning human thymus tissue from embryonic stem cells in the laboratory. The researchers showed that, in mice, the tissue can be used to foster the development of white blood cells the body needs to mount healthy immune responses and to prevent harmful autoimmune reactions. The scientists who developed the thymus cells — which caused the proliferation and maturation of functioning immune cells...
https://www.biyologlar.com/stem-cell-based-strategy-boosts-immune-system-in-mice -
Scientists discover how 'jumping genes' help black truffles adapt to their environment
Black truffles, also known as Périgord truffles, grow in symbiosis with the roots of oak and hazelnut trees. In the world of haute cuisine, they are expensive and highly prized. In the world of epigenetics, however, the fungi (Tuber melanosporum) are of major interest for another reason: their unique pattern of DNA methylation, a biochemical process that chemically modifies nucleic acids without changing their sequence. Epigenetics is the study of changes in gene expression caused by...
https://www.biyologlar.com/scientists-discover-how-jumping-genes-help-black-truffles-adapt-to-their-environment -
Scientists reconstruct ancient impact that dwarfs dinosaur-extinction blast
Picture this: A massive asteroid almost as wide as Rhode Island and about three to five times larger than the rock thought to have wiped out the dinosaurs slams into Earth. The collision punches a crater into the planet's crust that's nearly 500 kilometers (about 300 miles) across: greater than the distance from Washington, D.C. to New York City, and up to two and a half times larger in diameter than the hole formed by the dinosaur-killing asteroid. Seismic waves bigger than any recorded...
https://www.biyologlar.com/scientists-reconstruct-ancient-impact-that-dwarfs-dinosaur-extinction-blast -
Simple technology makes CRISPR gene editing cheaper
University of California, Berkeley, researchers have discovered a much cheaper and easier way to target a hot new gene editing tool, CRISPR-Cas9, to cut or label DNA. The CRISPR-Cas9 technique, invented three years ago at UC Berkeley, has taken genomics by storm, with its ability to latch on to a very specific sequence of DNA and cut it, inactivating genes with ease. This has great promise for targeted gene therapy to cure genetic diseases, and for discovering the causes of disease. The...
https://www.biyologlar.com/simple-technology-makes-crispr-gene-editing-cheaper -
Stem cell breakthrough could set up future transplant therapies
A new method for creating stem cells for the human liver and pancreas, which could enable both cell types to be grown in sufficient quantities for clinical use, has been developed by scientists. Using the technique, researchers have for the first time been able to grow a pure, self-renewing population of stem cells specific to the human foregut, the upper section of the human digestive system. These so-called "Foregut stem cells" could then be developed further to produce liver or pancreatic...
https://www.biyologlar.com/stem-cell-breakthrough-could-set-up-future-transplant-therapies -
New stem cells go back further
One of the obstacles to employing human embryonic stem cells for medical use lies in their very promise: They are born to rapidly differentiate into other cell types.
https://www.biyologlar.com/new-stem-cells-go-back-further -
Enzyme controlling metastasis of breast cancer identified
Researchers at the University of California, San Diego School of Medicine have identified an enzyme that controls the spread of breast cancer. The findings, reported in the current issue of PNAS, offer hope for the leading cause of breast cancer mortality worldwide. An estimated 40,000 women in America will die of breast cancer in 2014, according to the American Cancer Society. "The take-home message of the study is that we have found a way to target breast cancer metastasis through a pathway...
https://www.biyologlar.com/enzyme-controlling-metastasis-of-breast-cancer-identified -
Scientists discover an on-off switch for aging cells
Scientists at the Salk Institute have discovered an on-and-off "switch" in cells that may hold the key to healthy aging. This switch points to a way to encourage healthy cells to keep dividing and generating, for example, new lung or liver tissue, even in old age. In our bodies, newly divided cells constantly replenish lungs, skin, liver and other organs. However, most human cells cannot divide indefinitely–with each division, a cellular timekeeper at the ends of chromosomes shortens. When...
https://www.biyologlar.com/scientists-discover-an-on-off-switch-for-aging-cells -
Researchers use human stem cells to create light-sensitive retina in a dish
Using a type of human stem cell, Johns Hopkins researchers say they have created a three-dimensional complement of human retinal tissue in the laboratory, which notably includes functioning photoreceptor cells capable of responding to light, the first step in the process of converting it into visual images.
https://www.biyologlar.com/researchers-use-human-stem-cells-to-create-light-sensitive-retina-in-a-dish -
Genome-wide search reveals new genes involved in long-term memory
A new study has identified genes involved in long-term memory in the worm as part of research aimed at finding ways to retain cognitive abilities during aging. The study, which was published in the journal Neuron, identified more than 750 genes involved in long-term memory, including many that had not been found previously and that could serve as targets for future research, said senior author Coleen Murphy, an associate professor of molecular biology and the Lewis-Sigler Institute for...
https://www.biyologlar.com/genome-wide-search-reveals-new-genes-involved-in-long-term-memory -
Long-term changes in dead wood reveal new forest dynamics
Healthy forest ecosystems need dead wood to provide important habitat for birds and mammals, but there can be too much of a good thing when dead wood fuels severe wildfires. A scientist with the U.S. Forest Service's Pacific Southwest Research Station (PSW) compared historic and recent data from a forest in California's central Sierra Nevada region to determine how logging and fire exclusion have changed the amounts and sizes of dead wood over time. Results were recently published in Forest...
https://www.biyologlar.com/long-term-changes-in-dead-wood-reveal-new-forest-dynamics -
New method to grow zebrafish embryonic stem cells can regenerate whole fish
Zebrafish, a model organism that plays an important role in biological research and the discovery and development of new drugs and cell-based therapies, can form embryonic stem cells (ESCs).
https://www.biyologlar.com/new-method-to-grow-zebrafish-embryonic-stem-cells-can-regenerate-whole-fish -
New Science paper calculates magnitude of plastic waste going into the ocean
A plastic grocery bag cartwheels down the beach until a gust of wind spins it into the ocean. In 192 coastal countries, this scenario plays out over and over again as discarded beverage bottles, food wrappers, toys and other bits of plastic make their way from estuaries, seashores and uncontrolled landfills to settle in the world's seas. How much mismanaged plastic waste is making its way from land to ocean has been a decades-long guessing game. Now, the University of Georgia's Jenna Jambeck...
https://www.biyologlar.com/new-science-paper-calculates-magnitude-of-plastic-waste-going-into-the-ocean -
Detecting HIV diagnostic antibodies with DNA nanomachines
New research may revolutionize the slow, cumbersome and expensive process of detecting the antibodies that can help with the diagnosis of infectious and auto-immune diseases such as rheumatoid arthritis and HIV. An international team of researchers have designed and synthetized a nanometer-scale DNA "machine" whose customized modifications enable it to recognize a specific target antibody. Their new approach, which they described this month in Angewandte Chemie, promises to support the...
https://www.biyologlar.com/detecting-hiv-diagnostic-antibodies-with-dna-nanomachines -
Wisconsin scientists find genetic recipe to turn stem cells to blood
The ability to reliably and safely make in the laboratory all of the different types of cells in human blood is one key step closer to reality.
https://www.biyologlar.com/wisconsin-scientists-find-genetic-recipe-to-turn-stem-cells-to-blood -
Role of telomeres in plant stem cells discovered
The role played by telomeres in mammalian cells has been known for several years. It is also known that these non-coding DNA sequences, which are found at the ends of the chromosomes, protect them and are necessary to ensure correct cell division.
https://www.biyologlar.com/role-of-telomeres-in-plant-stem-cells-discovered -
Epigenetic signatures that differentiate triple-negative breast cancers
The new study, published in Nature Communications, compares the breast cancer DNA 'methylome' with that of healthy individuals. The methylome provides a new picture of the genome and shows how it is epigenetically 'decorated' with methyl groups, a process known as DNA 'methylation'.
https://www.biyologlar.com/epigenetic-signatures-that-differentiate-triple-negative-breast-cancers -
Wheat disease-resistance gene identified, potential to save billions
A gene that can prevent some of the most important wheat diseases has been identified--creating the potential to save more than a billion dollars in lost production in Australia alone each year. In a global collaboration including the University of Sydney's Plant Breeding Institute (PBI), the CSIRO, CIMMYT (Mexico), University of Newcastle, Chinese Academy of Sciences and the Norwegian University of Life Sciences, the gene Lr67 has been identified as providing resistance to three of the most...
https://www.biyologlar.com/wheat-disease-resistance-gene-identified-potential-to-save-billions -
New brain mapping reveals unknown cell types
Using a process known as single cell sequencing, scientists at Karolinska Institutet have produced a detailed map of cortical cell types and the genes active within them. The study, which is published in the journal 'Science', marks the first time this method of analysis has been used on such a large scale on such complex tissue. The team studied over three thousand cells, one at a time, and even managed to identify a number of hitherto unknown types. "If you compare the brain to a fruit...
https://www.biyologlar.com/new-brain-mapping-reveals-unknown-cell-types -
Scientists create functional liver cells from stem cells
The liver plays a critical role in human metabolism. As the gatekeeper of the digestive track, this massive organ is responsible for drug breakdown and is therefore the first to be injured due to overdose or misuse. Evaluating this drug-induced liver injury is a critical part of pharmaceutical drug discovery and must be carried out on human liver cells. Regretfully, human liver cells, called hepatocytes, are in scarce supply as they can only be isolated from donated organs. Now, in research...
https://www.biyologlar.com/scientists-create-functional-liver-cells-from-stem-cells -
Why some neurons 'outsource' their cell body
Nerve cells come in very different shapes. Researchers at the Bernstein Center Berlin now reveal why, in insects, the cell body is usually located at the end of a separate extension. Using mathematical models, they show that this increases the strength of electrical signal transmission at no additional energetic cost. Nerve cells follow a functional design: They receive input signals over more or less ramified cell branches (dendrites), which they forward to other nerve cells along an...
https://www.biyologlar.com/why-some-neurons-outsource-their-cell-body -
Closing the case on an ancient archeological mystery
Climate change may be responsible for the abrupt collapse of civilization on the fringes of the Tibetan Plateau around 2000 B.C. WSU archaeologist Jade D'Alpoim Guedes and an international team of researchers found that cooling global temperatures at the end of the Holocene Climatic Optimum, a 4,000 year period of warm weather, would have made it impossible for ancient people on the Tibetan Plateau to cultivate millet, their primary food source. Guedes' team's research recently was published...
https://www.biyologlar.com/closing-the-case-on-an-ancient-archeological-mystery -
Brazilian beef industry moves to reduce its destruction of rain forests
Expansion of cattle pastures has led to the destruction of huge swaths of rain forest in Brazil, home to the world's largest herd of commercial beef cattle. But a new study led by the University of Wisconsin-Madison's Holly Gibbs shows that market-driven "zero deforestation agreements" have dramatically influenced the behavior of ranchers and the slaughterhouses to which they sell. Publishing today [May 12, 2015] in the journal Conservation Letters, the research team - including other...
https://www.biyologlar.com/brazilian-beef-industry-moves-to-reduce-its-destruction-of-rain-forests -
Nano-walkers take speedy leap forward with first rolling DNA-based motor
Physical chemists have devised a rolling DNA-based motor that's 1,000 times faster than any other synthetic DNA motor, giving it potential for real-world applications, such as disease diagnostics. Nature Nanotechnology is publishing the finding. "Unlike other synthetic DNA-based motors, which use legs to 'walk' like tiny robots, ours is the first rolling DNA motor, making it far faster and more robust," says Khalid Salaita, the Emory University chemist who led the research. "It's like the...
https://www.biyologlar.com/nano-walkers-take-speedy-leap-forward-with-first-rolling-dna-based-motor -
Are embryonic stem cells and artificial stem cells equivalent?
Harvard Stem Cell Institute (HSCI) researchers at Massachusetts General Hospital and Harvard Medical School have found new evidence suggesting some human induced pluripotent stem cells are the 'functional equivalent' of human embryonic stem cells, a finding that may begin to settle a long running argument. The findings were published this week in Nature Biotechnology. From 1998 until 2007 embryonic stem cells (ES cells) were the only human cells known with the potential to become any other...
https://www.biyologlar.com/are-embryonic-stem-cells-and-artificial-stem-cells-equivalent -
How an RNA gene silences a whole chromosome
Researchers at Caltech have discovered how an abundant class of RNA genes, called long non-coding RNAs (lncRNAs, pronounced link RNAs) can regulate key genes. By studying an important lncRNA, called Xist, the scientists identified how this RNA gathers a group of proteins and ultimately prevents women from having an extra functional X-chromosome--a condition in female embryos that leads to death in early development. These findings mark the first time that researchers have uncovered the detailed...
https://www.biyologlar.com/how-an-rna-gene-silences-a-whole-chromosome -
Great Barrier Reef marine reserves combat coral disease
A new and significant role for marine reserves on the Great Barrier Reef has been revealed, with researchers finding the reserves reduce the prevalence of coral diseases. It's been known for some time that marine reserves are important for maintaining and enhancing fish stocks, but this is the first time marine reserves have been shown to enhance coral health on the Great Barrier Reef. Researchers from the ARC Centre of Excellence for Coral Reef Studies at James Cook University found that...
https://www.biyologlar.com/great-barrier-reef-marine-reserves-combat-coral-disease -
Unpacking embryonic pluripotency
Researchers at EMBL's European Bioinformatics Institute (EMBL-EBI) and the Wellcome Trust- Medical Research Council Cambridge Stem Cell Institute at the University of Cambridge have identified factors that spark the formation of pluripotent cells.
https://www.biyologlar.com/unpacking-embryonic-pluripotency -
Evrim ve Yeni Türlerin Oluşumu
Günümüzde türleşme,ayrı bir bilim dalı haline gelmiştir.Sınıflandırmada zorunlu bir rolü olmamakla beraber,türleşme bilimi,taksonominin bir alt birimi olarak kabul edilebilir.Türleşme çeşitleri: 1) Irklardan yeni türlere:Genel olarak bir türün,birbirinden belirgin şekilde farklı olan populasyonları ırk olarak nitelendirilir.Taksonomistler ırk kavramı yerine,bir türün içerisinde farklı populasyonları nitelendirmek için alttür,varyete ve subvaryete...
https://www.biyologlar.com/evrim-ve-yeni-turlerin-olusumu-1 -
Discovery of an unexpected function of a protein linked to neurodegenerative diseases
Until today, the proteins known as ubiquitin receptors have been associated mainly with protein degradation, a basic cell cleaning process. A new function now described for the protein dDsk2 by the team headed by Ferran Azorín, group leader at the Institute for Research in Biomedicine (IRB Barcelona) and CSIC research professor, links ubiquitin receptors for the first time with the regulation of gene expression. This discovery, published today in Nature Communications, opens up a double...
https://www.biyologlar.com/discovery-of-an-unexpected-function-of-a-protein-linked-to-neurodegenerative-diseases -
Discovery of an unexpected function of a protein linked to neurodegenerative diseases
Until today, the proteins known as ubiquitin receptors have been associated mainly with protein degradation, a basic cell cleaning process. A new function now described for the protein dDsk2 by the team headed by Ferran Azorín, group leader at the Institute for Research in Biomedicine (IRB Barcelona) and CSIC research professor, links ubiquitin receptors for the first time with the regulation of gene expression. This discovery, published today in Nature Communications, opens up a double...
https://www.biyologlar.com/discovery-of-an-unexpected-function-of-a-protein-linked-to-neurodegenerative-diseases