Toplam 399 içerik listeleniyor
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Function of mysterious RNAs may often lie in their genes
Scientists from Penn Medicine and other institutions unlock a mystery about 'long non-coding RNAs'. A new genetic clue discovered by a team co-led by a researcher at the Perelman School of Medicine at the University of Pennsylvania is shedding light on the functions of the mysterious "long non-coding RNAs" (lncRNAs). These molecules are transcribed from genes and are often abundant in cells, yet they do not code for proteins. Their functions have been almost entirely unknown--and in recent...
https://www.biyologlar.com/function-of-mysterious-rnas-may-often-lie-in-their-genes-haber-8132 -
Degenerating neurons respond to gene therapy treatment for Alzheimer's disease
Degenerating neurons in patients with Alzheimer's disease (AD) measurably responded to an experimental gene therapy in which nerve growth factor (NGF) was injected into their brains, report researchers at University of California, San Diego School of Medicine in the current issue of JAMA Neurology.
https://www.biyologlar.com/degenerating-neurons-respond-to-gene-therapy-treatment-for-alzheimer-aposs-disease-haber-8762 -
Gene therapy clips out heart failure causing gene mutations
This image shows the heart failure gene editing process. Gene therapy can clip out genetic material linked to heart failure and replace it with the normal gene in human cardiac cells, according to a study led by researchers from the Cardiovascular Research Center at Icahn School of Medicine at Mount Sinai. The study is published in the April 29 edition of Nature Communications.
https://www.biyologlar.com/gene-therapy-clips-out-heart-failure-causing-gene-mutations-haber-8764 -
New American Chemical Society podcast: Genetically-engineered spider silk for gene therapy
A new episode in the American Chemical Society's (ACS) award-winning "Global Challenges/Chemistry Solutions" podcast series spins a real-life tale in which spider silk shows promise for overcoming a major barrier to the use of gene therapy in everyday medicine.
https://www.biyologlar.com/new-american-chemical-society-podcast-genetically-engineered-spider-silk-for-gene-therapy-haber-8767 -
Yeni çalışma sonuçlarına göre D vitamini soğuktan ve Gripten koruyor!
Yeni bir araştırmaya göre, D vitamini takviyesi soğuk algınlığı ve grip de dahil olmak üzere akut solunum yolu enfeksiyonlarına karşı özellikle çok eksik kişilerde korunmaya yardımcı olabilir.
https://www.biyologlar.com/yeni-calisma-sonuclarina-gore-d-vitamini-soguktan-ve-gripten-koruyor -
Yeni çalışma sonuçlarına göre D vitamini soğuktan ve Gripten koruyor!
Yeni bir araştırmaya göre, D vitamini takviyesi soğuk algınlığı ve grip de dahil olmak üzere akut solunum yolu enfeksiyonlarına karşı özellikle çok eksik kişilerde korunmaya yardımcı olabilir.
https://www.biyologlar.com/yeni-calisma-sonuclarina-gore-d-vitamini-soguktan-ve-gripten-koruyor -
CAR T-Hücrelerinin Güvenliğini Arttırmak için Yeni Fikirler
Romatoid artritin tedavisi için onaylanan ilaçlar, immünoterapiden kaynaklanan ciddi yan etkilerden sorumlu moleküller olan sitokinleri bloke ediyor ve farelerde semptomları azaltıyor.
https://www.biyologlar.com/car-t-hucrelerinin-guvenligini-arttirmak-icin-yeni-fikirler -
CAR T-Hücrelerinin Güvenliğini Arttırmak için Yeni Fikirler
Romatoid artritin tedavisi için onaylanan ilaçlar, immünoterapiden kaynaklanan ciddi yan etkilerden sorumlu moleküller olan sitokinleri bloke ediyor ve farelerde semptomları azaltıyor.
https://www.biyologlar.com/car-t-hucrelerinin-guvenligini-arttirmak-icin-yeni-fikirler -
Tedavide ‘’Kök Hücre’’
Vücudumuzda yaşlanan ve ölen hücrelerin yerlerine yenileri oluşturulmaktadır. Bununla birlikte, yabancı antijenlerle savaşmak için vücut özel savunma hücreleri de üretmektedir. Gözümüzdeki hücreler görme, pankreastaki hücreler salgı, akciğerdeki hücreler solunum için farklılaşmaktadır.
https://www.biyologlar.com/tedavide-kok-hucre -
Tedavide ‘’Kök Hücre’’
Vücudumuzda yaşlanan ve ölen hücrelerin yerlerine yenileri oluşturulmaktadır. Bununla birlikte, yabancı antijenlerle savaşmak için vücut özel savunma hücreleri de üretmektedir. Gözümüzdeki hücreler görme, pankreastaki hücreler salgı, akciğerdeki hücreler solunum için farklılaşmaktadır.
https://www.biyologlar.com/tedavide-kok-hucre -
FİTOTERAPİ Bitkilerle tedavi
Fitoterapi, bitkilerin bilimsel temele dayalı akılcı bir yaklaşımla hastalıkların tedavisi veya önlenmesinde kullanımını anlamına gelmektedir. Bitki ve Tedavi sözcüklerinden oluşan fitoterapi, terimi ilk kez, Fransız hekim Henri Leclerc(1870-1955) tarafından `La Presse Medical` adlı dergide, 1939 yılında kullanılmış olsa da bitkilerin tedavide kullanılışı aslında insanlığın ortaya çıkışı ile başlar. İlk insanlar, bitki ve hayvanları izleyerek tedavi...
https://www.biyologlar.com/fitoterapi-bitkilerle-tedavi -
KÖK HÜCRELERE BAKIŞ:TANIMLAR, KAVRAMLAR ve SINIFLANDIRMALAR
İki binli yıllarla beraber kök hücrelerin rejeneratif tıp (yenileyici tıp) alanındaki öneminin giderek arttığını ve tıbbın geleceğini şekillendirme potansiyelini gözlemlemekteyiz.
https://www.biyologlar.com/kok-hucrelere-bakistanimlar-kavramlar-ve-siniflandirmalar -
Neden Taze Sebze ve Meyve Yemeliyiz?
Taze sebze ve meyvelerin denizciler, kaşifler ve üniversite öğrencileri için önemi
https://www.biyologlar.com/neden-taze-sebze-ve-meyve-yemeliyiz -
Neden Taze Sebze ve Meyve Yemeliyiz?
Taze sebze ve meyvelerin denizciler, kaşifler ve üniversite öğrencileri için önemi
https://www.biyologlar.com/neden-taze-sebze-ve-meyve-yemeliyiz -
Hayvan embriyonik organizatörler şimdi insan hücrelerinde keşfedildi
Canlı, aşılanmış bir civciv embriyosunda insan embriyonik kök hücreleri (kırmızı)I. MARTIN ET AL., NATURE , 2018
https://www.biyologlar.com/hayvan-embriyonik-organizatorler-simdi-insan-hucrelerinde-kesfedildi -
Hayvan embriyonik organizatörler şimdi insan hücrelerinde keşfedildi
Canlı, aşılanmış bir civciv embriyosunda insan embriyonik kök hücreleri (kırmızı)I. MARTIN ET AL., NATURE , 2018
https://www.biyologlar.com/hayvan-embriyonik-organizatorler-simdi-insan-hucrelerinde-kesfedildi -
Şizofreniye Dair Her Şey!
Günlük hayatımızda, sıkça duymuş olduğumuz psikolojik bozukluk olan ‘’Şizofreni’’ hakkında ne biliyoruz? Şizofreni genetik mi? Şizofreni bulaşıcı mı? Şizofreni hastası saldırgan mı? Gelin bu sorulara cevap verelim ve doğru bilinen yanlışlara el atalım.
https://www.biyologlar.com/sizofreniye-dair-her-sey -
Şizofreniye Dair Her Şey!
Günlük hayatımızda, sıkça duymuş olduğumuz psikolojik bozukluk olan ‘’Şizofreni’’ hakkında ne biliyoruz? Şizofreni genetik mi? Şizofreni bulaşıcı mı? Şizofreni hastası saldırgan mı? Gelin bu sorulara cevap verelim ve doğru bilinen yanlışlara el atalım.
https://www.biyologlar.com/sizofreniye-dair-her-sey -
Pancreas stem cell discovery may lead to new diabetes treatments
Stem cells in the adult pancreas have been identified that can be turned into insulin producing cells, a finding that means people with type 1 diabetes might one day be able to regenerate their own insulin-producing cells. The discovery was made by scientists from the Walter and Eliza Hall Institute and provides further evidence that stem cells don't only occur in the embryo. The ability to produce the hormone insulin is crucial for controlling blood sugar (glucose) levels. In people with...
https://www.biyologlar.com/pancreas-stem-cell-discovery-may-lead-to-new-diabetes-treatments -
Bir Prion Hastalığı: Ölümcül Ailesel Uykusuzluk
İlk FFI raporlarının tamamı İtalyan ailelerde olmasına rağmen, şu anda Birleşik Krallık, Avrupa, Amerika Birleşik Devletleri, Finlandiya, Avustralya, Çin ve Japonya'dan en az 27 FFI aile bildirilmektedir.
https://www.biyologlar.com/bir-prion-hastaligi-olumcul-ailesel-uykusuzluk -
Bir Prion Hastalığı: Ölümcül Ailesel Uykusuzluk
İlk FFI raporlarının tamamı İtalyan ailelerde olmasına rağmen, şu anda Birleşik Krallık, Avrupa, Amerika Birleşik Devletleri, Finlandiya, Avustralya, Çin ve Japonya'dan en az 27 FFI aile bildirilmektedir.
https://www.biyologlar.com/bir-prion-hastaligi-olumcul-ailesel-uykusuzluk -
Bir Prion Hastalığı: Ölümcül Ailesel Uykusuzluk
İlk FFI raporlarının tamamı İtalyan ailelerde olmasına rağmen, şu anda Birleşik Krallık, Avrupa, Amerika Birleşik Devletleri, Finlandiya, Avustralya, Çin ve Japonya'dan en az 27 FFI aile bildirilmektedir.
https://www.biyologlar.com/bir-prion-hastaligi-olumcul-ailesel-uykusuzluk -
Y Kromozomu
Bütün insanlarda X veya Y kromozomlarından birisi mutlaka bulunurken, kadınlarda "46, XX"; erkeklerde "46, XY" normal karyotip olarak bulunur.
https://www.biyologlar.com/y-kromozomu-1 -
Magnetic nanoparticles could be key to effective immunotherapy
In recent years, researchers have hotly pursued immunotherapy, a promising form of treatment that relies on harnessing and training the body's own immune system to better fight cancer and infection. Now, results of a study led by Johns Hopkins investigators suggests that a device composed of a magnetic column paired with custom-made magnetic nanoparticles may hold a key to bringing immunotherapy into widespread and successful clinical use. A summary of the research, conducted in mouse and human...
https://www.biyologlar.com/magnetic-nanoparticles-could-be-key-to-effective-immunotherapy -
Stem-cell approach shows promise for Duchenne muscular dystrophy
Researchers have shown that transplanting stem cells derived from normal mouse blood vessels into the hearts of mice that model the pathology associated with Duchenne muscular dystrophy (DMD) prevents the decrease in heart function associated with DMD. Their findings appear in the journal Stem Cells Translational Medicine. Duchenne muscular dystrophy is a genetic disorder caused by a mutation in the gene for dystrophin, a protein that anchors muscle cells in place when they contract. Without...
https://www.biyologlar.com/stem-cell-approach-shows-promise-for-duchenne-muscular-dystrophy -
Kene İle Bulaşan Hastalıklar
ÖZET Parazitlerin neden olduğu hastalıklar önemli sağlık problemidir. Endoparazit ve ektoparaziter hastalıklar mevcuttur. Kenelerle bulaşan hastalıklar en sık görülen vektör kaynaklı hastalıklardır. Keneler bakteri, virüs spiroket, protozoa, nematod ve toksinler gibi patojenleri yayabilir ve böylece ektoparaziter kaynaklı hastalıklara sebep olurlar. Ülkemizde keneler için iklim koşulları, bitki örtüsü ve yüzey şekli bakımından uygun koşullar vardır. Bu...
https://www.biyologlar.com/kene-ile-bulasan-hastaliklar -
Stem cell breakthrough could set up future transplant therapies
A new method for creating stem cells for the human liver and pancreas, which could enable both cell types to be grown in sufficient quantities for clinical use, has been developed by scientists. Using the technique, researchers have for the first time been able to grow a pure, self-renewing population of stem cells specific to the human foregut, the upper section of the human digestive system. These so-called "Foregut stem cells" could then be developed further to produce liver or pancreatic...
https://www.biyologlar.com/stem-cell-breakthrough-could-set-up-future-transplant-therapies -
Small molecule acts as on-off switch for nature's antibiotic factory
Scientists have identified the developmental on-off switch for Streptomyces, a group of soil microbes that produce more than two-thirds of the world's naturally derived antibiotic medicines. Their hope now would be to see whether it is possible to manipulate this switch to make nature's antibiotic factory more efficient. The study, appearing August 28 in Cell, found that a unique interaction between a small molecule called cyclic-di-GMP and a larger protein called BldD ultimately controls...
https://www.biyologlar.com/small-molecule-acts-as-on-off-switch-for-natures-antibiotic-factory -
Stanford researchers genetically engineer yeast to produce opioids
For thousands of years, people have used yeast to ferment wine, brew beer and leaven bread. Now researchers at Stanford have genetically engineered yeast to make painkilling medicines, a breakthrough that heralds a faster and potentially less expensive way to produce many different types of plant-based medicines. Writing today in Science, the Stanford engineers describe how they reprogrammed the genetic machinery of baker's yeast so that these fast-growing cells could convert sugar into...
https://www.biyologlar.com/stanford-researchers-genetically-engineer-yeast-to-produce-opioids -
New stem cells go back further
One of the obstacles to employing human embryonic stem cells for medical use lies in their very promise: They are born to rapidly differentiate into other cell types.
https://www.biyologlar.com/new-stem-cells-go-back-further -
Enzyme controlling metastasis of breast cancer identified
Researchers at the University of California, San Diego School of Medicine have identified an enzyme that controls the spread of breast cancer. The findings, reported in the current issue of PNAS, offer hope for the leading cause of breast cancer mortality worldwide. An estimated 40,000 women in America will die of breast cancer in 2014, according to the American Cancer Society. "The take-home message of the study is that we have found a way to target breast cancer metastasis through a pathway...
https://www.biyologlar.com/enzyme-controlling-metastasis-of-breast-cancer-identified -
Researchers use human stem cells to create light-sensitive retina in a dish
Using a type of human stem cell, Johns Hopkins researchers say they have created a three-dimensional complement of human retinal tissue in the laboratory, which notably includes functioning photoreceptor cells capable of responding to light, the first step in the process of converting it into visual images.
https://www.biyologlar.com/researchers-use-human-stem-cells-to-create-light-sensitive-retina-in-a-dish -
Ascaris lumbricoides
Ascaris lumbricoides is otherwise known as the large intestinal roundworm of humans. It looks a lot like a large earthworm, but the two are not related. The earthworm is an annelid; it lives in the soil, feeding on organic debris. A. lumbricoides is a parasitic nematode, or roundworm; adults are found only in the intestines of humans, feeding on intestinal contents as they flow past. If you were to compare the two very carefully, you would note that the earthworm has little tufts of bristles...
https://www.biyologlar.com/ascaris-lumbricoides -
New method to grow zebrafish embryonic stem cells can regenerate whole fish
Zebrafish, a model organism that plays an important role in biological research and the discovery and development of new drugs and cell-based therapies, can form embryonic stem cells (ESCs).
https://www.biyologlar.com/new-method-to-grow-zebrafish-embryonic-stem-cells-can-regenerate-whole-fish -
Kimerler, Kediler ve Diğer Genetik Tuhaflıklar
Hayır, bu bir fotoğraf hilesi değil. Bu gördüğünüz kedicik, aslında bir Kimer olmayan, ama bu yazıyı yazmak için bana esin kaynağı olan Venüs. (Kaynak: Facebook)
https://www.biyologlar.com/kimerler-kediler-ve-diger-genetik-tuhafliklar -
The Role of Insulin in the Human Body
Developed and produced by http://www.MechanismsinMedicine.com Animation Description: This patient-friendly animation describes the main role of insulin in the human body. When food is ingested, it travels along the digestive tract where it is broken down into its component nutrients in order to be absorbed into the bloodstream. One such nutrient is glucose, a simple sugar. Glucose gets absorbed by the stomach and intestines and then enters the bloodstream. It travels through the circulation...
https://www.biyologlar.com/the-role-of-insulin-in-the-human-body -
Wisconsin scientists find genetic recipe to turn stem cells to blood
The ability to reliably and safely make in the laboratory all of the different types of cells in human blood is one key step closer to reality.
https://www.biyologlar.com/wisconsin-scientists-find-genetic-recipe-to-turn-stem-cells-to-blood -
Snake venom helps hydrogels stop the bleeding
A nanofiber hydrogel infused with snake venom may be the best material to stop bleeding quickly, according to Rice University scientists. The hydrogel called SB50 incorporates batroxobin, a venom produced by two species of South American pit viper. It can be injected as a liquid and quickly turns into a gel that conforms to the site of a wound, keeping it closed, and promotes clotting within seconds. Rice chemist Jeffrey Hartgerink, lead author Vivek Kumar and their colleagues reported their...
https://www.biyologlar.com/snake-venom-helps-hydrogels-stop-the-bleeding -
Amniotic stem cells demonstrate healing potential
Rice University and Texas Children's Hospital scientists are using stem cells from amniotic fluid to promote the growth of robust, functional blood vessels in healing hydrogels.
https://www.biyologlar.com/amniotic-stem-cells-demonstrate-healing-potential -
Kanser Tedavisinde Yeni Silahlar
İnsanlık, bildiğimiz kadarı ile, yazılı tarih boyunca kendi tarihi kadar eski ve bir o kadar da ürkütücü kanserle mücadele etmiş ve hala bu mücadelesine devam etmekte. M.Ö. 3000 yıllarında yazıldığı tahmin edilen eski Mısır metinlerinde meme ülserlerinin (o zaman henüz kanser kelimesi literatürde yoktu) koterle yakılarak alındığı anlatılıyor. Günümüzde ise kanser hastaları radyoterapi, kemoterapi ve cerrahi müdahaleler ile tedavi edilmeye çalışılmakta....
https://www.biyologlar.com/kanser-tedavisinde-yeni-silahlar -
Stem cells might heal damaged lungs
Collectively, such diseases of the airways as emphysema, bronchitis, asthma and cystic fibrosis are the second leading cause of death worldwide.
https://www.biyologlar.com/stem-cells-might-heal-damaged-lungs -
Neurons constantly rewrite their DNA
Johns Hopkins scientists have discovered that neurons are risk takers: They use minor "DNA surgeries" to toggle their activity levels all day, every day. Since these activity levels are important in learning, memory and brain disorders, the researchers think their finding will shed light on a range of important questions. A summary of the study will be published online in the journal Nature Neuroscience on April 27. "We used to think that once a cell reaches full maturation, its DNA is totally...
https://www.biyologlar.com/neurons-constantly-rewrite-their-dna -
Discovery of an unexpected function of a protein linked to neurodegenerative diseases
Until today, the proteins known as ubiquitin receptors have been associated mainly with protein degradation, a basic cell cleaning process. A new function now described for the protein dDsk2 by the team headed by Ferran Azorín, group leader at the Institute for Research in Biomedicine (IRB Barcelona) and CSIC research professor, links ubiquitin receptors for the first time with the regulation of gene expression. This discovery, published today in Nature Communications, opens up a double...
https://www.biyologlar.com/discovery-of-an-unexpected-function-of-a-protein-linked-to-neurodegenerative-diseases -
Discovery of an unexpected function of a protein linked to neurodegenerative diseases
Until today, the proteins known as ubiquitin receptors have been associated mainly with protein degradation, a basic cell cleaning process. A new function now described for the protein dDsk2 by the team headed by Ferran Azorín, group leader at the Institute for Research in Biomedicine (IRB Barcelona) and CSIC research professor, links ubiquitin receptors for the first time with the regulation of gene expression. This discovery, published today in Nature Communications, opens up a double...
https://www.biyologlar.com/discovery-of-an-unexpected-function-of-a-protein-linked-to-neurodegenerative-diseases -
Novel stem cell line avoids risk of introducing transplanted tumors
Human pluripotent stem cells (hPSC) can become any type of cell in the adult body, offering great potential in disease modeling, drug discovery and creating replacement cells for conditions ranging from cardiovascular to Alzheimer's disease. But that promise comes with a risk: the possibility that transplanted hPSCs might also develop as unwanted tumors. In a new study published November 10, 2015 in the online journal eLIFE, researchers at University of California, San Diego School of Medicine...
https://www.biyologlar.com/novel-stem-cell-line-avoids-risk-of-introducing-transplanted-tumors -
Discovery of an embryonic switch for cancer stem cell generation
An international team of scientists, headed by researchers at UC San Diego School of Medicine and UC San Diego Moores Cancer Center, report that decreases in a specific group of proteins trigger changes in the cancer microenvironment that accelerate growth and development of therapy-resistant cancer stem cells (CSCs). The discovery suggests the basis for a potential new therapeutic approach to eradicate blood cancers, which affect more than 1.1 million Americans. In fact, researchers found...
https://www.biyologlar.com/discovery-of-an-embryonic-switch-for-cancer-stem-cell-generation -
Forensic botany uses plant DNA to trace crimes
Sam Houston State University is advancing the field of forensic botany with the publication of two recent studies that use marijuana DNA to link drug supplies and pollen DNA to aid in forensic investigations. In an article published in the International Journal of Legal Medicine, faculty and students from the Department of Forensic Science report that they developed a test to individualize samples of marijuana that could be used to link drugs across cases. The study examined 11 cases...
https://www.biyologlar.com/forensic-botany-uses-plant-dna-to-trace-crimes -
Combining adult stem cells with hormone may speed bone fracture healing
A combination of adult stem cells and parathyroid hormone significantly increased new bone formation in laboratory animals and may speed the healing process for human bone fractures caused by osteoporosis, a new study shows. The study is published online by Molecular Therapy, a peer-reviewed journal in the Nature Publishing Group. Researchers used a combination of mesenchymal stem cells, which are derived from bone marrow taken from adults, and parathyroid hormone, also called PTH, which...
https://www.biyologlar.com/combining-adult-stem-cells-with-hormone-may-speed-bone-fracture-healing -
New GTEx findings show how DNA differences influence gene activity, disease susceptibility
Researchers funded by the National Institutes of Health Genotype-Tissue Expression (GTEx) project have created a new and much-anticipated data resource to help establish how differences in an individual's genomic make-up can affect gene activity and contribute to disease. The new resource will enable scientists to examine the underlying genomics of many different human tissues and cells at the same time, and promises to open new avenues to the study and understanding of human biology. GTEx...
https://www.biyologlar.com/new-gtex-findings-show-how-dna-differences-influence-gene-activity-disease-susceptibility -
Hacking the programs of cancer stem cells
All tumor cells are the offspring of a single, aberrant cell, but they are not all alike. Only a few retain the capacity of the original cell to create an entire tumor.
https://www.biyologlar.com/hacking-the-programs-of-cancer-stem-cells