Toplam 85 içerik listeleniyor
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UW team stores digital images in DNA -- and retrieves them perfectly
Technology companies routinely build sprawling data centers to store all the baby pictures, financial transactions, funny cat videos and email messages its users hoard. But a new technique developed by University of Washington and Microsoft researchers could shrink the space needed to store digital data that today would fill a Walmart supercenter down to the size of a sugar cube. The team of computer scientists and electrical engineers has detailed one of the first complete systems to encode,...
https://www.biyologlar.com/uw-team-stores-digital-images-in-dna-and-retrieves-them-perfectly-haber-8723 -
Embriyonik fare böbreğinin gelişim süreci / embryonic mouse kidney developing
Embriyonik fare böbreğinin gelişim süreci / embryonic mouse kidney developing
https://www.biyologlar.com/embriyonik-fare-bobreginin-gelisim-sureci-embryonic-mouse-kidney-developing -
Study documents catastrophic collapse of Sahara's wildlife
A new study led by the Wildlife Conservation Society and Zoological Society or London warns that the world's largest tropical desert, the Sahara, has suffered a catastrophic collapse of its wildlife populations. The study by more than 40 authors representing 28 scientific organizations assessed 14 desert species and found that a shocking half of those are regionally extinct or confined to one percent or less of their historical range. A chronic lack of studies across the region due to past and...
https://www.biyologlar.com/study-documents-catastrophic-collapse-of-saharas-wildlife -
Highly efficient CRISPR knock-in in mouse
Genome editing using CRISPR/Cas system has enabled direct modification of the mouse genome in fertilized mouse eggs, leading to rapid, convenient, and efficient one-step production of knockout mice without embryonic stem cells. In contrast to the ease of targeted gene deletion, the complementary application, called targeted gene cassette insertion or knock-in, in fertilized mouse eggs by CRISPR/Cas mediated genome editing still remains a tough challenge. Professor Kohichi Tanaka and Dr. Tomomi...
https://www.biyologlar.com/highly-efficient-crispr-knock-in-in-mouse -
Stem cells + nanofibers = Promising nerve research
Every week in his clinic at the University of Michigan, neurologist Joseph Corey, M.D., Ph.D., treats patients whose nerves are dying or shrinking due to disease or injury.
https://www.biyologlar.com/stem-cells-nanofibers-promising-nerve-research -
Scientists reconstruct ancient impact that dwarfs dinosaur-extinction blast
Picture this: A massive asteroid almost as wide as Rhode Island and about three to five times larger than the rock thought to have wiped out the dinosaurs slams into Earth. The collision punches a crater into the planet's crust that's nearly 500 kilometers (about 300 miles) across: greater than the distance from Washington, D.C. to New York City, and up to two and a half times larger in diameter than the hole formed by the dinosaur-killing asteroid. Seismic waves bigger than any recorded...
https://www.biyologlar.com/scientists-reconstruct-ancient-impact-that-dwarfs-dinosaur-extinction-blast -
Stem cell breakthrough could set up future transplant therapies
A new method for creating stem cells for the human liver and pancreas, which could enable both cell types to be grown in sufficient quantities for clinical use, has been developed by scientists. Using the technique, researchers have for the first time been able to grow a pure, self-renewing population of stem cells specific to the human foregut, the upper section of the human digestive system. These so-called "Foregut stem cells" could then be developed further to produce liver or pancreatic...
https://www.biyologlar.com/stem-cell-breakthrough-could-set-up-future-transplant-therapies -
New stem cells go back further
One of the obstacles to employing human embryonic stem cells for medical use lies in their very promise: They are born to rapidly differentiate into other cell types.
https://www.biyologlar.com/new-stem-cells-go-back-further -
Stem cells from teeth can make brain-like cells
University of Adelaide researchers have discovered that stem cells taken from teeth can grow to resemble brain cells, suggesting they could one day be used in the brain as a therapy for stroke.
https://www.biyologlar.com/stem-cells-from-teeth-can-make-brain-like-cells -
Chip-based technology enables reliable direct detection of Ebola virus
A team led by researchers at UC Santa Cruz has developed chip-based technology for reliable detection of Ebola virus and other viral pathogens. The system uses direct optical detection of viral molecules and can be integrated into a simple, portable instrument for use in field situations where rapid, accurate detection of Ebola infections is needed to control outbreaks. Laboratory tests using preparations of Ebola virus and other hemorrhagic fever viruses showed that the system has the...
https://www.biyologlar.com/chip-based-technology-enables-reliable-direct-detection-of-ebola-virus -
New Science paper calculates magnitude of plastic waste going into the ocean
A plastic grocery bag cartwheels down the beach until a gust of wind spins it into the ocean. In 192 coastal countries, this scenario plays out over and over again as discarded beverage bottles, food wrappers, toys and other bits of plastic make their way from estuaries, seashores and uncontrolled landfills to settle in the world's seas. How much mismanaged plastic waste is making its way from land to ocean has been a decades-long guessing game. Now, the University of Georgia's Jenna Jambeck...
https://www.biyologlar.com/new-science-paper-calculates-magnitude-of-plastic-waste-going-into-the-ocean -
Epigenetic signatures that differentiate triple-negative breast cancers
The new study, published in Nature Communications, compares the breast cancer DNA 'methylome' with that of healthy individuals. The methylome provides a new picture of the genome and shows how it is epigenetically 'decorated' with methyl groups, a process known as DNA 'methylation'.
https://www.biyologlar.com/epigenetic-signatures-that-differentiate-triple-negative-breast-cancers -
How an RNA gene silences a whole chromosome
Researchers at Caltech have discovered how an abundant class of RNA genes, called long non-coding RNAs (lncRNAs, pronounced link RNAs) can regulate key genes. By studying an important lncRNA, called Xist, the scientists identified how this RNA gathers a group of proteins and ultimately prevents women from having an extra functional X-chromosome--a condition in female embryos that leads to death in early development. These findings mark the first time that researchers have uncovered the detailed...
https://www.biyologlar.com/how-an-rna-gene-silences-a-whole-chromosome -
Shiny fish skin inspires nanoscale light reflectors
A nature-inspired method to model the reflection of light from the skin of silvery fish and other organisms may be possible, according to Penn State researchers. Such a technique may be applicable to developing better broadband reflectors and custom multi-spectral filters for a wide variety of applications, including advanced optical coatings for glass, laser protection, infrared imaging systems, optical communication systems and photovoltaics, according to Douglas Werner, John L. and...
https://www.biyologlar.com/shiny-fish-skin-inspires-nanoscale-light-reflectors -
Combining adult stem cells with hormone may speed bone fracture healing
A combination of adult stem cells and parathyroid hormone significantly increased new bone formation in laboratory animals and may speed the healing process for human bone fractures caused by osteoporosis, a new study shows. The study is published online by Molecular Therapy, a peer-reviewed journal in the Nature Publishing Group. Researchers used a combination of mesenchymal stem cells, which are derived from bone marrow taken from adults, and parathyroid hormone, also called PTH, which...
https://www.biyologlar.com/combining-adult-stem-cells-with-hormone-may-speed-bone-fracture-healing -
New GTEx findings show how DNA differences influence gene activity, disease susceptibility
Researchers funded by the National Institutes of Health Genotype-Tissue Expression (GTEx) project have created a new and much-anticipated data resource to help establish how differences in an individual's genomic make-up can affect gene activity and contribute to disease. The new resource will enable scientists to examine the underlying genomics of many different human tissues and cells at the same time, and promises to open new avenues to the study and understanding of human biology. GTEx...
https://www.biyologlar.com/new-gtex-findings-show-how-dna-differences-influence-gene-activity-disease-susceptibility -
Researchers build molecule that could significantly reduce brain damage in stroke victims
Research teams separated by 14 hours and 9,000 miles have collaborated to advance prospective treatment for the world's second-leading cause of death. University of Nebraska-Lincoln chemists partnered with medical researchers from the National University of Singapore to develop a molecule that can inhibit an enzyme linked with the onset of stroke. Most strokes occur when a disruption of blood flow prevents oxygen and glucose from reaching brain tissue, ultimately killing neurons and other...
https://www.biyologlar.com/researchers-build-molecule-that-could-significantly-reduce-brain-damage-in-stroke-victims -
Small molecules change biological clock rhythm
A team of chemists and biologists at the Institute of Transformative Bio-Molecules (ITbM), Nagoya University have succeeded in finding new molecules that change the circadian rhythm in mammals by applying synthetic chemistry methods, which makes use of highly selective metal catalysts. Most living organisms have a biological clock with an approximately 24-hour circadian rhythm, which regulates important body functions such as sleep/wake cycles, hormone secretion, and metabolism. Disruption of...
https://www.biyologlar.com/small-molecules-change-biological-clock-rhythm -
Mantis shrimp inspires next generation of ultra-strong materials
This is the herringbone structure of the outer layer (impact region) of the mantis shrimp dactyl club.
https://www.biyologlar.com/mantis-shrimp-inspires-next-generation-of-ultra-strong-materials -
Mantis shrimp inspires next generation of ultra-strong materials
This is the herringbone structure of the outer layer (impact region) of the mantis shrimp dactyl club.
https://www.biyologlar.com/mantis-shrimp-inspires-next-generation-of-ultra-strong-materials -
Why human egg cells don't age well
When egg cells form with an incorrect number of chromosomes--a problem that increases with age--the result is usually a miscarriage or a genetic disease such as Down syndrome. Now, researchers at the RIKEN Center for Developmental Biology in Japan have used a novel imaging technique to pinpoint a significant event that leads to these types of age-related chromosomal errors. Published in Nature Communications, the study shows that as egg cells mature in older women, paired copies of matching...
https://www.biyologlar.com/why-human-egg-cells-dont-age-well -
Hybrid cells cause chaos around cancers
Rice University researchers have built a simulation to show how cancerous tumors manipulate blood-vessel growth for their own benefit. Like all cells, those in tumors need access to the body's fine network of blood vessels to bring them oxygen and carry away waste. Tumors have learned to game the process called angiogenesis in which new vessels sprout from existing ones, like branches from a tree. But some details have been hidden until now. The ability to stop tumors through...
https://www.biyologlar.com/hybrid-cells-cause-chaos-around-cancers -
Breakthrough in scaling up life-changing stem cell production
Scientists have discovered a new method of creating human stem cells which could solve the big problem of the large-scale production needed to fully realise the potential of these remarkable cells for understanding and treating disease.
https://www.biyologlar.com/breakthrough-in-scaling-up-life-changing-stem-cell-production -
Lowly 'new girl' chimps form stronger female bonds
Low-ranking "new girl" chimpanzees seek out other gal pals with similar status, finds a new study of social relationships in the wild apes. The study is available online and is scheduled to appear in the July 2015 issue of the journal Animal Behaviour. Unlike most primates, female chimps are loners compared to males. "They spend about half their time alone or with dependent kids," said Duke University research scientist Steffen Foerster, who co-authored the study. "Chimpanzee females' more...
https://www.biyologlar.com/lowly-new-girl-chimps-form-stronger-female-bonds -
Disease that causes blindness in children tied to new gene
Northwestern Medicine and University of Wisconsin-Madison (UW) scientists have identified a gene that causes severe glaucoma in children.
https://www.biyologlar.com/disease-that-causes-blindness-in-children-tied-to-new-gene -
Quantum dots with impermeable shell: A powerful tool for nanoengineering
Images of ZnO quantum dots prepared by the Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw, taken by transmission electron microscopy. False colors.
https://www.biyologlar.com/quantum-dots-with-impermeable-shell-a-powerful-tool-for-nanoengineering -
Quantum dots with impermeable shell: A powerful tool for nanoengineering
Images of ZnO quantum dots prepared by the Institute of Physical Chemistry of the Polish Academy of Sciences in Warsaw, taken by transmission electron microscopy. False colors.
https://www.biyologlar.com/quantum-dots-with-impermeable-shell-a-powerful-tool-for-nanoengineering -
In some genetic cases of microcephaly, stem cells fail to launch
In a very severe, genetic form of microcephaly, stem cells in the brain fail to divide, according to a new Columbia University Medical Center study that may provide important clues to understanding how the Zika virus affects the developing brain.
https://www.biyologlar.com/in-some-genetic-cases-of-microcephaly-stem-cells-fail-to-launch -
New mechanisms of self-organization in living cells
Chromosome is a structure inside the cell nucleus that carries a large part of the genetic information and is responsible for its storage, transfer and implementation. Chromosome is formed from a very long DNA molecule - a double chain of a plurality of genes. Given that the diameter of the cell nucleus is usually around hundredth of a millimeter or even less, while the total length of DNA constituting human genome is about two meters, it is clear that DNA must be packaged very...
https://www.biyologlar.com/new-mechanisms-of-self-organization-in-living-cells -
Nematode inside nematode
An Antarctic nematode developing within another nematode.
https://www.biyologlar.com/nematode-inside-nematode -
'Tree of life' for 2.3 million species released
A first draft of the "tree of life" for the roughly 2.3 million named species of animals, plants, fungi and microbes -- from platypuses to puffballs -- has been released. A collaborative effort among eleven institutions, the tree depicts the relationships among living things as they diverged from one another over time, tracing back to the beginning of life on Earth more than 3.5 billion years ago. Tens of thousands of smaller trees have been published over the years for select branches of the...
https://www.biyologlar.com/tree-of-life-for-2-3-million-species-released -
Zooming in on bacterial weapons in 3-D
The plague, bacterial dysentery, and cholera have one thing in common: These dangerous diseases are caused by bacteria which infect their host using a sophisticated injection apparatus. Through needle-like structures, they release molecular agents into their host cell, thereby evading the immune response. Researchers at the Max Planck Institute for Biophysical Chemistry in Göttingen in cooperation with colleagues at the Max Planck Institute for Infection Biology in Berlin and the University of...
https://www.biyologlar.com/zooming-in-on-bacterial-weapons-in-3-d -
Second contagious form of cancer found in Tasmanian devils
Transmissible cancers -- cancers which can spread between individuals by the transfer of living cancer cells -- are believed to arise extremely rarely in nature.
https://www.biyologlar.com/second-contagious-form-of-cancer-found-in-tasmanian-devils -
Genetic code of red blood cells discovered
Eight days. That's how long it takes for skin cells to reprogram into red blood cells. Researchers at Lund University in Sweden, together with colleagues at Center of Regenerative Medicine in Barcelona, have successfully identified the four genetic keys that unlock the genetic code of skin cells and reprogram them to start producing red blood cells instead. "We have performed this experiment on mice, and the preliminary results indicate that it is also possible to reprogram skin cells from...
https://www.biyologlar.com/genetic-code-of-red-blood-cells-discovered -
Genetic code of red blood cells discovered
Eight days. That's how long it takes for skin cells to reprogram into red blood cells. Researchers at Lund University in Sweden, together with colleagues at Center of Regenerative Medicine in Barcelona, have successfully identified the four genetic keys that unlock the genetic code of skin cells and reprogram them to start producing red blood cells instead. "We have performed this experiment on mice, and the preliminary results indicate that it is also possible to reprogram skin cells from...
https://www.biyologlar.com/genetic-code-of-red-blood-cells-discovered -
Shape-shifting molecule tricks viruses into mutating themselves to death
A newly developed spectroscopy method is helping to clarify the poorly understood molecular process by which an anti-HIV drug induces lethal mutations in the virus's genetic material. The findings from the University of Chicago and the Massachusetts Institute of Technology could bolster efforts to develop the next generation of anti-viral treatments. Viruses can mutate rapidly in order to adapt to environmental pressure. This feature also helps them become resistant to anti-viral drugs. But...
https://www.biyologlar.com/shape-shifting-molecule-tricks-viruses-into-mutating-themselves-to-death -
DNA breaks in nerve cells' ancestors cluster in specific genes
The genome of developing brain cells harbors 27 clusters or hotspots where its DNA is much more likely to break in some places than others, researchers from the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital, Harvard Medical School, and the Howard Hughes Medical Institute report in the journal Cell. Those hotspots appear in genes associated with brain tumors and a number of neurodevelopmental and neuropsychiatric conditions, raising new questions about these...
https://www.biyologlar.com/dna-breaks-in-nerve-cells-ancestors-cluster-in-specific-genes -
DNA breaks in nerve cells' ancestors cluster in specific genes
The genome of developing brain cells harbors 27 clusters or hotspots where its DNA is much more likely to break in some places than others, researchers from the Program in Cellular and Molecular Medicine (PCMM) at Boston Children's Hospital, Harvard Medical School, and the Howard Hughes Medical Institute report in the journal Cell. Those hotspots appear in genes associated with brain tumors and a number of neurodevelopmental and neuropsychiatric conditions, raising new questions about these...
https://www.biyologlar.com/dna-breaks-in-nerve-cells-ancestors-cluster-in-specific-genes -
NIH-funded study establishes genomic data set on Lassa virus
An international team of researchers has developed the largest genomic data set in the world on Lassa virus (LASV). The new genomic catalog contains nearly 200 viral genomes collected from patient samples in Sierra Leone and Nigeria, as well as field samples from the major animal reservoir, or host, of Lassa virus--the rodent Mastomys natalensis, also called the multimammate rat. The researchers show that LASV strains cluster into four major groups based on geographic location, with three in...
https://www.biyologlar.com/nih-funded-study-establishes-genomic-data-set-on-lassa-virus -
Genetic regulation of the thymus function identified
A single thymic epithelial cell (red) in contact with developing T cells (white).
https://www.biyologlar.com/genetic-regulation-of-the-thymus-function-identified -
Genetic regulation of the thymus function identified
A single thymic epithelial cell (red) in contact with developing T cells (white).
https://www.biyologlar.com/genetic-regulation-of-the-thymus-function-identified -
Penn study reveals how fish control microbes through their gills
Oriol Sunyer, a professor at the University of Pennsylvania School of Veterinary Medicine, has described fish as "an open gut swimming."
https://www.biyologlar.com/penn-study-reveals-how-fish-control-microbes-through-their-gills -
Human kidney progenitors isolated, offering new clues to cell renewal
In a first-of-its-kind look at human kidney development, researchers at The Saban Research Institute of Children's Hospital Los Angeles have isolated human nephron progenitor (NP) cells.
https://www.biyologlar.com/human-kidney-progenitors-isolated-offering-new-clues-to-cell-renewal -
Supercomputing the evolution of a model flower
Scientists using supercomputers found genes sensitive to cold and drought in a plant help it survive climate change. These findings increase basic understanding of plant adaptation and can be applied to improve crops.
https://www.biyologlar.com/supercomputing-the-evolution-of-a-model-flower -
How a cold gets into cells
Cold viruses cause us irritation by penetrating into our cells and transporting their RNA into the cytoplasma of the infected cells. This is the only way they can multiply.
https://www.biyologlar.com/how-a-cold-gets-into-cells -
Fruitful collaboration yields insight on the tomato genome
Plant biologist Julin Maloof met fellow researcher Neelima Sinha while beginning his career at the University of California, Davis. Both interested in plant morphology and natural variation,
https://www.biyologlar.com/fruitful-collaboration-yields-insight-on-the-tomato-genome -
Researchers map Zika's routes to the developing fetus
Zika virus infects numerous primary cell types and explants of the human placenta, suggesting placental and paraplacental routes of virus transmission.
https://www.biyologlar.com/researchers-map-zikas-routes-to-the-developing-fetus -
Researchers map Zika's routes to the developing fetus
Zika virus infects numerous primary cell types and explants of the human placenta, suggesting placental and paraplacental routes of virus transmission.
https://www.biyologlar.com/researchers-map-zikas-routes-to-the-developing-fetus -
Mouse antibodies pinpoint Zika's weak spots
This image shows the mapping of the three distinct Zika virus DIII epitopes onto the mature virion
https://www.biyologlar.com/mouse-antibodies-pinpoint-zikas-weak-spots